Why H2O2

Hydrogen Peroxide Decontamination Overview

When cleaning your modular cleanroom environment or other work areas requiring standards of sterility, the quickest and most effective way to inactivate microorganisms and other pathogens is by hydrogen peroxide decontamination. Hydrogen peroxide decontamination, also known as VHP or vapourised hydrogen peroxide decontamination, is used in industries whereby aseptic manufacturing procedures are used to sterilise a product or environment, such as in critical care and isolation wards in hospitals, pharmaceutical cleanrooms, operating theatres, fermentation suites, and research labs.

Hydrogen Peroxide Vapour

Vapourised hydrogen peroxide is a solution of water and hydrogen peroxide designed to decontaminate by coating surfaces and objects in an ultra-thin layer of micro-condensation of hydrogen peroxide vapour, undetectable to the naked eye. When passed over a vapouriser the liquid solution becomes a vapour in concentrations of 140 – 1400 parts per million. The vapourised hydrogen peroxide is left to circulate throughout the cleanroom or closed environment for a set period of time, after which it is broken down into oxygen and water via a catalytic converter.

The micro-condensation left by the hydrogen peroxide vapour provides optimal inactivation conditions for microorganisms. Using high velocity gas distribution nozzles and a vapour generator, all objects and surfaces within a cleanroom or clean environment are exposed uniformly to the hydrogen peroxide vapour.

As vaporized hydrogen peroxide naturally biodegrades into water and oxygen, it’s considered to be “residue free” and one of the most environmentally friendly methods of decontamination out there. Once cleanroom airflow and natural biodegradation have dropped hydrogen peroxide vapor levels within the environment to a level safe for humans (< 1ppm) personnel can resume cleanroom functions.

The Benefits Of Hydrogen Peroxide Decontamination

Aseptic processing cleanroom environments utilize hydrogen peroxide decontamination procedures in order to sterilise the environment without causing potential damage to products through radiation decontamination. This is especially true of the pharmaceutical industry, where radiation could potentially denature samples and medications. Hydrogen peroxide decontamination offers a safe method of sterilising a cleanroom without the use of radiation.

Hydrogen peroxide vapour produces no noxious fumes and naturally biodegrades into harmless molecules, making it safe for use and transport.

Hydrogen peroxide decontamination is effective against a wide variety of pathogens such as spores and fungi, viruses, bacteria, as well as MRSA and is capable of reducing these contaminants below detectable levels within minutes.

Hydrogen peroxide vapour biodegrades quickly and naturally, forming oxygen and water as a by-product. It is considered “no residue” and non-polluting.

The process of hydrogen peroxide decontamination does not damage surfaces or equipment within a cleanroom or clean environment, allowing personnel to return quickly and easily after decontamination.

Hydrogen peroxide decontamination easily inactivates the following cleanroom contaminants:

  • Aspergillus Expansum
  • Aspergillus Niger
  • Aspergillus Parasiticus
  • Aspergillus Restrictus
  • Aspergillus Sydowii Cladosporium
  • Bacillus
  • Bacillus Atrophaeus
  • Bacillus Stearothermophilus
  • Bacillus Subtilis
  • Cladosporiodes Type 1
  • Cladosporium Cladosporiodes
  • Cladosporium Sphaerospermen
  • Escherichia Coli
  • Penicillium Atramentosum
  • Penicillium Chrysogenum
  • Penicillium Citrinum
  • Pseudomonas
  • Pseudomonas Aeruginosa
  • Salmonella Choleraesius
  • Serratia Marcescens
  • Staphylococcus Aureus
  • Stachybotrys Chartarum
  • Trichophyton Mentagrophyte